Lijia Wang, Xiao Huang, Jun Jiang
Mar 6, 2006
Citations
1
Influential Citations
56
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 1,1,3,3-Tetramethylguanidine acts as a highly effective catalyst for cyanosilylation of various ketones and aldehydes to the corresponding cyanohydrin trimethylsilyl ethers in up to 99% yield. The reaction proceeds smoothly with 0.1 mol % catalyst loading at 25 °C under solvent-free conditions.