N. Aksenov, A. Aksenov, Lidiya A. Prityko
Apr 15, 2022
Citations
0
Influential Citations
1
Citations
Journal
ACS Omega
Abstract
A facile and highly efficient method for the preparation of 2-(3-oxoindolin-2-ylidene)acetonitriles from 4-(2-aminophenyl)-4-oxo-2-phenylbutanenitriles is described. The featured transformation operates via nucleophilic intramolecular cyclization and involves oxidation of the aniline moiety. Overall, this modification allowed for the improvement of yields and expansion of the reaction scope.