Cyclization reactions of 4-(3′-butenyl)azetidin-2-one a route to the carbopenam ring system

doi:10.1016/S0040-4039(01)86770-8

Paper

Cyclization reactions of 4-(3′-butenyl)azetidin-2-one a route to the carbopenam ring system

Published 1979 · T. Aida, R. Legault, D. Dugat

Tetrahedron Letters

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20

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Abstract

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Study Snapshot

Cyclization of 4-(3′-butenyl)azetidin-2-one leads to the formation of bicyclic -lactams with the carbopenam ring skeleton, with PhSBr giving a mixture of cyclization and addition products.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Cyclization reactions of 4-(3′-butenyl)azetidin-2-one a route to the carbopenam ring system

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References

A new synthesis of beta-lactams.

Combining heteroatomic nucleophiles and oxidative ligand transfer in Fp(olefin) complexes allows for facile and stereospecific synthesis of mono- and bicyclic beta-lactams from olefins.

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