Cytotoxic xanthones from the roots of Mesua ferrea L.

doi:10.1016/j.phytochem.2018.10.008

Paper

Cytotoxic xanthones from the roots of Mesua ferrea L.

Published 2019 · Arnon Chukaew, S. Saithong, Sasitorn Chusri

Phytochemistry

Q1 SJR score

25

Citations

2

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Abstract

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In Vitro Study

Study Snapshot

The roots of Mesua ferrea L. contain five undescribed xanthones and 33 known xanthones, with known 1,5,6-trihydroxyxanthone showing cytotoxicity against A375, PC-3, and HaCaT cell lines.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Cytotoxic xanthones from the roots of Mesua ferrea L.

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References

Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand.

Medicinal plants from Thailand may help develop novel treatments to overcome the blood-brain barrier and multidrug-resistance in tumor cells mediated by P-glycoprotein.

A new xanthone derivative from twigs of Garcinia nobilis

The twigs of Garcinia nobilis contain a new xanthone derivative and 15 known compounds, with compounds 5 and 11 showing moderate cytotoxic activity against human cervix carcinoma cells.

A new bisanthraquinone and cytotoxic xanthones from Cratoxylum cochinchinense

The new bisanthraquinone and two modified xanthones from Cratoxylum cochinchinense stems show strong cytotoxicity against human epidermoid carcinoma and breast cancer cell lines.

Xanthones from Swertia mussotii and Their α-Glycosidase Inhibitory Activities

1,3,5,8-tetrahydroxyxanthone is the best inhibitor of -glucosidase in Swertia mussotii, while O-glycosylated xanthones are poor inhibitors.

Effects of Mesua ferrea Leaf and Fruit Extracts on Growth and Morphology of Staphylococcus aureus

Mesua ferrea leaf and fruit extracts show good antibacterial activity against Staphylococcus aureus, but may potentially harm the bacterial morphology.

Physicochemical and antioxidant properties of Bangladeshi honeys stored for more than one year

Multifloral Bangladeshi honeys have higher antioxidant properties due to higher levels of phenolics, flavonoids, AEAC, DPPH, and FRAP compared to monofloral honeys.

In-vivo antioxidant and immunomodulatory activity of mesuol isolated from Mesua ferrea L. seed oil.

Mesuol, a compound isolated from Mesua ferrea L. seed oil, shows immunomodulatory activity, increasing antibody titer values and restoring hematological profile in cyclophosphamide-induced immunosuppression models.

WinGX and ORTEP for Windows: an update

WinGX and ORTEP for Windows are complete programs for treating small-molecule single-crystal diffraction data, with new features and improved functionality.

Xanthones from roots of Calophyllum thwaitesii and their bioactivity

Calophyllum thwaitesii root extract shows antifungal and antioxidant properties, with four active xanthones identified and the presence of methylating enzymes in the root stem.

Citations