Paper

Design, synthesis and biological evaluation of 2-methyl-(1,1'-biphenyl)-pyrimidine conjugates.

Published Aug 15, 2020 · DOI · A. Chen, Dong Wu, Jia Shi

Bioorganic & medicinal chemistry letters

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Abstract

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In Vitro Study

Study Snapshot

Novel compounds with 2-methyl-(1,1'-biphenyl)-pyrimidine conjugates show strong anti-cancer effects, particularly against HepG2 cells and HT-29 cells.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Design, synthesis and biological evaluation of 2-methyl-(1,1'-biphenyl)-pyrimidine conjugates.

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