Reinhard A. Diller, H. Riepl, Oliver Rose
2009
Citations
1
Influential Citations
6
Citations
Journal
Beer in Health and Disease Prevention
Abstract
Abstract Desmethylxanthohumol is a chalcone-type compound isolated from hops. It is present in extracts in a concentration of about 1/5 of the xanthohumol content. It isomerizes easily in aequous media like beer to a mixture of 6- and 8-prenylnaringenin, a phytoestrogen with hormonal activity. Desmethylxanthohumol is a powerful apoptosis inducing agent in lymphoid leukemic cell assays and it acts as a chemoprotective compound activating oxidation and excretion of harmful xenobiotics.