V. Yadav, V. Sriramurthy
Apr 30, 2001
Citations
0
Influential Citations
4
Citations
Journal
Tetrahedron
Abstract
Abstract The steric effects in the geometry on cation-chelation predict the experimental π -selectivity of 1-oxa-4-thiaspiro[4.5]decan-6-one, 1-oxa-4-thiaspiro[4.4]nonan-6-one, 1-thiaspiro[4.4] nonan-6-one, and 1-oxaspiro[4.4]nonan-6-one. The reversal in the selectivity of 1-oxa-4-thiaspiro[4.4]nonan-6-one on reduction with ( i -Bu) 2 AlH appears to be a direct consequence of the steric interactions arising from the large i -Bu substituents. The antiperiplanar effects are not as significant as the steric effects.