Afsaneh L. Sanati
Sep 1, 2017
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0
Influential Citations
46
Citations
Journal
International Journal of Electrochemical Science
Abstract
Methyldopa is one the important catecholamines used for treatment of high blood pressure. In this study, a nanocomposite electrode was made using graphene quantum dots (GQD) and 1-butyl-3methylimidazolium hexafluorophosphate (1B3MIPF6) in a carbon paste matrix (GQD/1B3MIPF6/CPE). The used GQD was synthesized and characterized using transmission electron microscopy (TEM). The electro-oxidation behavior of Methyldopa was investigated on the surface of GQD/1B3MIPF6/CPE and finally it was used as a working electrode for the electrochemical determination of Methyldopa in some pharmaceutical and biological samples. The results showed an improvement of ~3.2 times in electro-oxidation peak of methyldopa in a dynamic linear range of 0.04750.0 μM (limit of detection 0.01 μM).