L. Tan, S. Bryant, R. Murray
Mar 12, 1988
Citations
0
Influential Citations
22
Citations
Quality indicators
Journal
The Lancet
Abstract
The haemodynamic effects of intravenous cyclizine, an antiemetic that is widely given with opioids in left ventricular failure and myocardial infarction, were studied in 11 patients with severe heart failure. Cyclizine significantly increased systemic and pulmonary arterial pressures, and right and left ventricular filling pressures, and negated the venodilatory effects of diamorphine. The use of cyclizine in patients with heart failure should, therefore, be avoided.