E. Tyumina, G. Bazhutin, E. Vikhareva
Mar 13, 2019
Citations
0
Influential Citations
5
Citations
Journal
IOP Conference Series: Materials Science and Engineering
Abstract
The non-steroidal anti-inflammatory drug diclofenac (2-[2-(2,6-dichloroanilino)phenyl] acetic acid) is one of the most frequently detected pharmaceuticals in the environment. The ability of actinobacteria of the genus Rhodococcus to biodegrade diclofenac (170 μΜ) as the sodium salt has been revealed. Cells of R. ruber IEGM 231 pregrown with diclofenac (1.7 μΜ) removed diclofenac (about 50% degradation) within 56 days in the presence of glucose. Diclofenac induced changes in the morphometric characteristics of rhodococci. The products of diclofenac biodegradation did not have pronounced phytotoxicity.