Andreia I. S. Almeida, Vera L. M. Silva, Artur M. S. Silva
Apr 1, 2012
Citations
0
Influential Citations
10
Citations
Journal
Synlett
Abstract
New syntheses of acridin-9(10 H)-oneswere developed. One involves a two-step transformation, namely theDiels-Alder -reactions of ( E)-1-methyl-2-styrylquinolin-4(1 H)-ones with N-methylmaleimidein refluxing toluene, followed by oxidation of the formed adducts.The second consists in an one-pot procedure using 1,2,4-trichlorobenzeneas solvent at 180 ˚C. The effect of microwave irraditionand Lewis acid catalysts in these cycloaddition -reactionswas also investigated.