Dihydro-beta-agarofuran sesquiterpenes and pentacyclic triterpenoids from the root bark of Osyris lanceolata.

doi:10.1021/np900597w

Paper

Dihydro-beta-agarofuran sesquiterpenes and pentacyclic triterpenoids from the root bark of Osyris lanceolata.

Published May 25, 2010 · Elizabeth M. O. Yeboah, R. Majinda, A. Kadziola

Journal of natural products

Q1 SJR score

16

Citations

2

Influential Citations

Full textSemantic Scholar

Abstract

Three new dihydro-beta-agarofuran polyesters, 1alpha,9beta-difuranoyloxy-2-oxodihydro-beta-agarofuran (1), 1alpha,9beta-difuranoyloxy-2-oxo-3-enedihydro-beta-agarofuran (2), and 1alpha,9beta-difuranoyloxydihydro-beta-agarofuran (3), have been isolated from the CHCl(3) extract of the root bark of Osyris lanceolata, together with two known pentacylic triterpenoids, 4 and 5. Compounds 1-5 did not scavenge the DPPH radical within 30 min of reaction time. All five compounds displayed antifungal activity against Candida albicans. Compounds 1, 3, 4, and 5 showed antibacterial activity against the Gram-positive Bacillus subtilis and Staphylococcus aureus and Gram-negative Escherichia coli and Pseudomonas aeruginosa, with 4 and 5 being the most active. Compound 2 displayed weak antibacterial activity only against Escherichia coli.

In Vitro Study

Study Snapshot

Osyris lanceolata root bark contains five compounds with antifungal and antibacterial properties, with compounds 4 and 5 showing the most activity against bacteria.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Dihydro-beta-agarofuran sesquiterpenes and pentacyclic triterpenoids from the root bark of Osyris lanceolata.

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References

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Radical Scavenging Activity and Total Phenolic Content of Extracts of the Root Bark of Osyris Lanceolata

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Four new sesquiterpene compounds were identified in the essential oil of east African sandalwood Osyris tenuifolia, including two with new sesquiterpene backbones.

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The EVAL-14 method effectively evaluates reflection intensity in challenging situations, such as anisotropic mosaicity, peak splitting, and interference from close neighbors.

Citations

The health benefits of santol fruits and bioactive products isolated from Sandoricum koetjape Merr.: A scoping review.

Santol fruits and other parts of the santol tree contain bioactive compounds with anti-inflammatory, anticancer properties, and potential for phytomedicine.

Pentacyclic Triterpenoids Isolated from Celastraceae: A Focus in the 13C-NMR Data

Celastraceae species are important plant sources of triterpenes with diverse biological activities, including antiviral, antimicrobial, analgesic, and cytotoxic properties against various tumor cell lines.

Leishmanicidal Activity of a Quinone Methide Triterpenoid from the roots of Senna spectabilis var. excelsa (Fabaceae)

Metabolite 1 from Senna spectabilis var. excelsa roots shows potent leishmanicidal activity against Leishmania amazonensis and L. brazilensis, comparable to miltefosine.

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Osyris quadripartita leaves show potential in pharmaceutical and cosmetic fields due to their antioxidant, anti-inflammatory, and cytotoxic properties.

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African sandalwood (Osyris lanceolata) is a hemiparasitic tree with fragrant wood, traditional uses, and various phytochemicals, making it a valuable resource for perfume and medicinal purposes.

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The Nepalese sandalwood Osyris wightiana contains bioactive compounds such as megastiigmanes, phenyl propanoid, benzyl alcohol, iridoid, and phenyl propanoid glycosides, which show potential as a new source

Five new agarofuran sesquiterpene polyesters from Osyris lanceolata

Five new agarofuran sesquiterpene polyesters were isolated from Osyris lanceolata root and stem bark, with their structures elucidated through IR, UV, MS, and NMR spectroscopy.