Paper
Dihydropyran-2-carboxylic acid, a novel bifunctional linker for the solid-phase synthesis of peptides containing a C-terminal alcohol
Published 1998 · H. Hsieh, Yinghan Wu, Shui-Tein Chen
Chemical Communications
Q1 SJR score
14
Citations
0
Influential Citations
Abstract
Dihydropyran-2-carboxylic acid, a novel compound used to link an amino alcohol and an amine resin, is utilised for the solid-phase synthesis of peptide alcohols via the Fmoc strategy; this bifunctional linker was effectively applied to the synthesis of Octreotide.
Study Snapshot
Dihydropyran-2-carboxylic acid effectively links amino alcohol and amine resin for the solid-phase synthesis of peptide alcohols, including Octreotide.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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