K. Srikanth, Thangaraju Murugesan, C. A. Kumar
2002
Citations
0
Influential Citations
26
Citations
Quality indicators
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Abstract
The effect of methanol extract of whole plants of Trichodesma indicum R. Br. has been investigated on sulphur dioxide (SO2) induced cough reflex in Swiss albino mice. The extract has demonstrated significant (p < 0.001) inhibition in frequency of cough in all the tested doses when compared with untreated control group. The effect persisted up to 90 min of its oral administration and also comparable to that of the effect exhibited by the standard drug (Codeine phosphate). This study confirmed the traditional use of this plant in the treatment of cough. Determination of underlying mechanism of beneficial effect is major topic requiring further comprehensive investigation.