Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK.

doi:10.1016/j.jnutbio.2008.09.002

Paper

DOI: 10.1016/j.jnutbio.2008.09.002

Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK.

Published Dec 1, 2009 · Yiqian Wang, M. Yao

The Journal of nutritional biochemistry

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Abstract

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In Vitro Study

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Chromium picolinate increases glucose uptake in insulin-resistant adipocytes through activation of p38 MAPK, independent of GLUT4 translocation.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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References

DOI: 10.1016/J.METABOL.2007.04.021

Effect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated rat.

Chromium picolinate treatment significantly improves metabolic risk factors and reduces microvascular complications in a high-fat, streptozotocin-treated rat model of type 2 diabetes mellitus.

2007·187citations·K. Şahin et al.·Metabolism: clinical and experimental

Metabolism: clinical and experimental

DOI: 10.2337/dc06-0996

Effect of Chromium Supplementation on Glucose Metabolism and Lipids

Chromium supplementation significantly improves glucose metabolism in patients with diabetes, but has no significant effect on lipid or glucose metabolism in people without diabetes.

2007·246citations·E. Balk et al.·Diabetes Care

Diabetes Care

DOI: 10.1897/05-494R.1

Evaluation of potential toxicity and bioavailability of chromium in sediments associated with chromite ore processing residue

Cr(III) can be present at highly elevated concentrations in sediments associated with chromite ore processing residue without causing sediment toxicity.

2006·31citations·D. Becker et al.·Environmental Toxicology and Chemistry

Environmental Toxicology and Chemistry

DOI: 10.1016/J.BBRC.2006.06.154

Chromium and vanadate combination increases insulin-induced glucose uptake by 3T3-L1 adipocytes.

Chromium and vanadate both enhance insulin-induced glucose uptake in adipocytes, but their combined effect is not additive, suggesting separate mechanisms of action for each nutrient.

2006·26citations·D. Brautigan et al.·Biochemical and biophysical research communications

Biochemical and biophysical research communications

DOI: 10.1210/ME.2005-0255

Chromium activates glucose transporter 4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism.

Chromium supplementation improves glucose tolerance and reduces cholesterol levels in adipocytes through a cholesterol-dependent mechanism.

2006·183citations·Guoli Chen et al.·Molecular endocrinology

Molecular endocrinology

Citations

DOI: 10.1063/5.0203858

Silk fibroin promotes H3K9me3 expression and chromatin reorganization to regulate endothelial cell proliferation

Silk fibroin promotes endothelial cell proliferation by increasing H3K9me3 levels, even under stress conditions, by reorganizing chromatin.

2024·0citations·Kaixiang Gao et al.·APL Bioengineering

APL Bioengineering

DOI: 10.1016/j.tox.2024.153800

Differential susceptibility of BRL cells with/without insulin resistance and the role of endoplasmic reticulum stress signaling pathway in response to acrylamide-exposure toxicity effects in vitro.

Acrylamide exposure causes severer toxicity in insulin-resistant BRL cells through overactivation of the endoplasmic reticulum stress signaling pathway.

2024·0citations·Yuchao Guo et al.·Toxicology

Toxicology

DOI: 10.4103/JAPTR.JAPTR_343_23

Test of insulin resistance in nondiabetic and streptozotocin-induced diabetic rats using glycosylated hemoglobin test and other interventions

Combining PGZ with Cr-GTF significantly lowers insulin levels and HOMA-IR levels in type 2 diabetes mellitus rats, suggesting potential benefits for treating the condition.

2024·1citation·Lina AlTamimi et al.·Journal of Advanced Pharmaceutical Technology & Research

Journal of Advanced Pharmaceutical Technology & Research

DOI: 10.3390/antiox12081572

A Comprehensive Review of the Impact of Chromium Picolinate on Testicular Steroidogenesis and Antioxidant Balance

Chromium picolinate may negatively impact testicular steroidogenesis and male fertility by inhibiting enzymes and inducing mutagenesis and apoptosis in Leydig cells.

2023·8citations·Rúben Moreira et al.·Antioxidants

Antioxidants

DOI: 10.1039/d1fo00267h

Protocatechuic acid influences immune-metabolic changes in the adipose tissue of pregnant women with gestational diabetes mellitus.

Protocatechuic acid, a major metabolite of anthocyanins, can stimulate glucose uptake and modulate inflammation in adipose tissue from pregnant women with gestational diabetes mellitus.

2021·4citations·Beatrice Scazzocchio et al.·Food & function

Food & function

DOI: 10.1016/J.ARABJC.2021.103236

Potential antidiabetic molecule involving a new chromium(III) complex of dipicolinic and metformin as a counter ion: Synthesis, structure, spectroscopy, and bioactivity in mice

The new chromium(III) complex with dipicolinic and metformin shows potential as a safe and effective antidiabetic agent for type 2 diabetes mellitus.

2021·3citations·Jin-long Dong et al.·Arabian Journal of Chemistry

Arabian Journal of Chemistry

DOI: 10.1007/s12011-021-02693-3

Effect of Chromium Supplementation on Blood Glucose and Lipid Levels in Patients with Type 2 Diabetes Mellitus: a Systematic Review and Meta-analysis

Chromium supplementation can reduce glycosylated hemoglobin levels in type 2 diabetic patients, but does not effectively improve fasting blood glucose or blood lipid levels.

2021·22citations·Fengyi Zhao et al.·Biological Trace Element Research

Biological Trace Element Research

DOI: 10.1111/1440-1681.13462

A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review

Chromium supplementation decreases oxidative stress in diabetes mellitus by increasing antioxidant enzyme activity and improving antioxidant indices.

2021·24citations·Fateme Kooshki et al.·Clinical and Experimental Pharmacology and Physiology

Clinical and Experimental Pharmacology and Physiology

DOI: 10.1016/j.micpath.2020.104276

Dietary infection of Enterobacter ludwigii causes fat accumulation and resulted in the diabetes-like condition in Drosophila melanogaster.

Enterobacter ludwigii infection in Drosophila melanogaster leads to fat accumulation and alters glucose metabolism, resulting in a diabetes-like condition.

2020·10citations·S. Priyadarsini et al.·Microbial pathogenesis

Microbial pathogenesis