M. Uchida, N. Kurihara, T. Fujita
Sep 1, 1974
Citations
0
Influential Citations
29
Citations
Journal
Pesticide Biochemistry and Physiology
Abstract
Abstract The biological effects of benzene hexachloride (BHC, 1,2,3,4,5,6-hexachlorocyclohexane) isomers, such as toxicity against yeasts, inhibition of beef brain Na + -K + -ATPase, and blocking action on conduction in cockroach nerve, were determined and compared with those shown by homologous alcohols and other molecules. Each type of biological activity correlated well with the physicochemical properties of the test compounds such as hydrophobicity (as defined by their partition coefficients in 1-octanol/H 2 O). The insecticidal action of γ-BHC showed little correspondence to Na + -K + -ATPase inhibition or to nerve blocking in insects.