Effects of nocistatin on nociceptin-induced impairment of learning and memory in mice.

doi:10.1016/S0014-2999(99)00003-5

Paper

DOI: 10.1016/S0014-2999(99)00003-5

Effects of nocistatin on nociceptin-induced impairment of learning and memory in mice.

Published Feb 19, 1999 · M. Hiramatsu, Kaori Inoue

European journal of pharmacology

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Highly Cited

Study Snapshot

Nociceptin impairs learning and memory in mice, but nocistatin improves this impairment without changing motor activity or response to electric shocks.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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References

DOI: 10.1038/29073

Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors

Mice lacking nociceptin receptors exhibit better memory and learning ability, possibly due to altered intracellular signal transduction systems in neurons.

1998·305citations·T. Manabe et al.·Nature

Nature

DOI: 10.1038/32660

Nocistatin, a peptide that blocks nociceptin action in pain transmission

Nocistatin, a peptide produced from the same precursor as nociceptin, blocks nociceptin-induced allodynia and hyperalgesia, and attenuates pain evoked by prostaglandin E2.

1998·232citations·E. Okuda‐Ashitaka et al.·Nature

Nature

DOI: 10.1038/sj.bjp.0701671

Reversion of muscarinic autoreceptor agonist‐induced acetylcholine decrease and learning impairment by dynorphin A (1–13), an endogenous κ‐opioid receptor agonist

Dynorphin A (1-13), an endogenous opioid receptor agonist, effectively reverses carbachol-induced learning and memory impairment in rats, potentially due to dysfunction of presynaptic cholinergic neurones through opioid receptors.

1998·29citations·M. Hiramatsu et al.·British Journal of Pharmacology

British Journal of Pharmacology

DOI: 10.1016/S0014-2999(97)01411-8

Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor.

Noc/oFQ, a neuropeptide with multiple functions, may have therapeutic applications in pain management and other conditions.

1997·385citations·J. Meunier·European journal of pharmacology

European journal of pharmacology

DOI: 10.1016/S0091-3057(96)00159-1

Effects of Dynorphin A (1-13) on Carbon Monoxide-Induced Delayed Amnesia in Mice

Dynorphin A (1-13) reverses carbon monoxide-induced delayed amnesia in mice by modulating the kappa opioid receptor-mediated neuronal system.

1997·57citations·M. Hiramatsu et al.·Pharmacology Biochemistry and Behavior

Pharmacology Biochemistry and Behavior

Citations

DOI: 10.3390/ijms241411713

Stress-Induced Changes in the Endogenous Opioid System Cause Dysfunction of Pain and Emotion Regulation

Stress-induced changes in the endogenous opioid system contribute to dysfunction in pain and emotion regulation, contributing to stress-induced psychiatric disorders and chronic pain.

2023·13citations·K. Nakamoto et al.·International Journal of Molecular Sciences

International Journal of Molecular Sciences

DOI: 10.29252/iau.30.2.107

The effect of agonist and antagonist of Nociceptine/Orphanin FQ receptor on seizure and cognitive dysfunction in experimental model of temporal lobe epilepsy in male rat

Pre-treatment with NOP receptor agonist and antagonist reduced seizures attacks and improved short-term spatial memory and tissue damage in rats with temporal lobe epilepsy.

2020·0citations·نیدا جمالی رئوفی et al.·Medical Sciences

Medical Sciences

DOI: 10.29252/iau.30.2.107

The effect of agonist and antagonist of Nociceptine/Orphanin FQ receptor on seizure and cognitive dysfunction in experimental model of temporal lobe epilepsy in male rat

Pre-treatment with NOP receptor agonist and antagonist reduced seizures attacks and improved short-term spatial memory and tissue damage in rats with temporal lobe epilepsy.

2020·0citations·N. Jamali-Raeufy et al.·MEDICAL SCIENCES JOURNAL

MEDICAL SCIENCES JOURNAL

DOI: 10.1523/ENEURO.0376-19.2020

Differential Modulation of Ventral Tegmental Area Circuits by the Nociceptin/Orphanin FQ System

The nociceptin/orphanin FQ system is primarily inhibitory in ventral tegmental area neurons, with different effects on dopaminergic pathways and neurobehavioral disorders.

2019·14citations·Joseph R. Driscoll et al.·eNeuro

eNeuro

DOI: 10.1007/164_2018_185

The Nociceptin/Orphanin FQ System and the Regulation of Memory.

The NOP receptor ligands can alter learning processes and memory consolidation, potentially affecting long-term memory through neuronal mechanisms in the hippocampus and amygdala.

2018·10citations·L. Moulédous·Handbook of experimental pharmacology

Handbook of experimental pharmacology

DOI: 10.1016/j.neuropharm.2017.07.006

Activation of nociceptin/orphanin FQ receptors inhibits contextual fear memory reconsolidation

Activating the nociceptin/orphanin FQ receptor system impairs reconsolidation of context-dependent aversive memories, potentially weakening maladaptive memories.

2017·18citations·K. Rekik et al.·Neuropharmacology

Neuropharmacology

DOI: 10.1016/j.pnpbp.2015.02.007

Nociceptin and the nociceptin receptor in learning and memory

Nociceptin and its receptor, the nociceptin receptor (NOP receptor), play a crucial role in learning and memory processes, with potential links to PTSD.

2015·35citations·R. Andero·Progress in Neuro-Psychopharmacology and Biological Psychiatry

Progress in Neuro-Psychopharmacology and Biological Psychiatry