[An emulsion based on 1-bromoperfluorooctane: X-ray contrast properties and mechanisms of X-ray contrasting].

Paper

[An emulsion based on 1-bromoperfluorooctane: X-ray contrast properties and mechanisms of X-ray contrasting].

Published Mar 1, 2007 · A. Sklifas, S. L. Chaplygina, D. Shekhtman

Biofizika

UNKNOWN SJR score

1

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0

Influential Citations

Semantic Scholar

Abstract

It has been shown that the emulsion of a mixture of the perfluorocarbons 1-bromoperfluorooctane and perfluoro[1-(4-methylcyclohexyl)piperidine], stabilized by egg yolk phospholipids, makes it possible to contrast rapidly (beginning with the 10th minute) and for a long time (up to 5 days) the tissues of various organs, such as liver, spleen, adrenal glands, heart, and the peritoneal part of the aorta. The roentgenograms of rat organs in in vivo experiments were evaluated by computer-assisted morphodensitometry. The contrasting of organs at early terms of the circulation of emulsion in the body is related to a high concentration of 1-bromoperfluorooctane in the blood flow, and the contrasting at later terms is related to the accumulation of emulsion particles by cells of the reticuloendothelial system.

Non-RCT

Animal Study

Study Snapshot

The emulsion of 1-bromoperfluorooctane and perfluoro[1-(4-methylcyclohexyl)piperidine, stabilized by egg yolk phospholipids, rapidly and effectively contrasts various organ tissues for up to 5 days, with early contrasting

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

[An emulsion based on 1-bromoperfluorooctane: X-ray contrast properties and mechanisms of X-ray contrasting].

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References

Citations

Application of perfluorocarbon emulsions for the administration of photosensitizing preparations into bone marrow stem cells

Perfluorocarbon emulsions with radachlorine nanoparticles can effectively kill bone marrow stem cells by destroying their cell membranes, potentially offering a promising treatment for bone marrow cancer.