Zhenhua Wu, Senzhi Zhao, David M Fash
Feb 7, 2017
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Influential Citations
39
Citations
Quality indicators
Journal
Journal of natural products
Abstract
In the decade since the discovery of englerin A (1) and its potent activity in cancer models, this natural product and its analogues have been the subject of numerous chemical, biological, and preclinical studies by many research groups. This review summarizes published findings and proposes further research directions required for entry of an englerin analogue into clinical trials for kidney cancer and other conditions.