S. Toniolo, F. Aricò, P. Tundo
Mar 14, 2014
Citations
0
Influential Citations
19
Citations
Journal
ACS Sustainable Chemistry & Engineering
Abstract
Alternative syntheses for the production of 3-benzyl-1,3-oxazinan-2-one are compared and evaluated employing green metrics. An environmental assessment has been performed using the algorithm recently developed by Andraos that takes into account the mass flows and the software EATOS that considers mass flows, environmental impacts of the substances involved, and waste produced. Strengths and critical spots of the environmental tools employed are also discussed. Data collected showed that the synthesis employing diethyl carbonate is the most promising one, having the lowest environmental impact.