Paper
Ethylene glycol promoted catalyst-free pseudo three-component green synthesis of bis(coumarin)s and bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s
Published May 24, 2016 · Sushama S. Kauthale, S. Tekale, K. M. Jadhav
Molecular Diversity
Q2 SJR score
26
Citations
0
Influential Citations
Abstract
An ethylene glycol promoted catalyst-free practically efficient and sustainable approach has been developed for the synthesis of several benzylidene-bis-(4-hydroxycoumarin)s and 4,$$4^{\prime }$$4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s by the pseudo three-component reaction of an aldehyde with 4-hydroxycoumarin and 3-methyl-1-phenylpyrazol-5-one, respectively. Inexpensive, non-toxic, and easily available ethylene glycol used as the reaction solvent and promoter renders an efficient protocol in terms of catalyst-free reaction conditions, short reaction time, high yield, practical utility, and green approach.
Study Snapshot
Ethylene glycol promotes catalyst-free, efficient, and sustainable synthesis of bis(coumarin)s and bis(3-methyl-1-phenyl-1H-pyrazol-5-ols, offering practical utility and a green approach.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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