B. Cowper, Tsz Mei Sze, B. Premdjee
Feb 5, 2015
Citations
0
Influential Citations
12
Citations
Journal
Chemical communications
Abstract
3/4-Mercaptobenzyl sulfonates were investigated as aryl thiol catalysts for native chemical ligation (NCL). Whilst catalysing NCL processes at a similar rate to 4-mercaptophenyl acetic acid (MPAA), the increased polarity and solubility of 3-mercaptobenzyl sulfonate in particular may favour its selection as NCL catalyst in many instances.