Exploring isoxsuprine hydrochloride binding with human serum albumin in the presence of folic acid and ascorbic acid using multispectroscopic and molecular modeling methods.

doi:10.1016/j.jphotobiol.2017.04.007

Paper

DOI: 10.1016/j.jphotobiol.2017.04.007

Exploring isoxsuprine hydrochloride binding with human serum albumin in the presence of folic acid and ascorbic acid using multispectroscopic and molecular modeling methods.

Published May 1, 2017 · Fereshteh Shiri, S. Shahraki, A. Shahriyar

Journal of photochemistry and photobiology. B, Biology

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Abstract

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In Vitro Study

Study Snapshot

Isoxsuprine hydrochloride increases binding to human serum albumin in the presence of ascorbic acid, while folic acid reduces it, potentially causing conformational and microenvironmental changes in the protein.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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