Exploring isoxsuprine hydrochloride binding with human serum albumin in the presence of folic acid and ascorbic acid using multispectroscopic and molecular modeling methods.

doi:10.1016/j.jphotobiol.2017.04.007

Paper

DOI: 10.1016/j.jphotobiol.2017.04.007

Exploring isoxsuprine hydrochloride binding with human serum albumin in the presence of folic acid and ascorbic acid using multispectroscopic and molecular modeling methods.

Published May 1, 2017 · Fereshteh Shiri, S. Shahraki, A. Shahriyar

Journal of photochemistry and photobiology. B, Biology

UNKNOWN SJR score

Citations

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

In Vitro Study

Study Snapshot

Isoxsuprine hydrochloride increases binding to human serum albumin in the presence of ascorbic acid, while folic acid reduces it, potentially causing conformational and microenvironmental changes in the protein.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Full text analysis coming soon...

References

DOI: 10.1080/07391102.2016.1243074

Assessment of the interaction procedure between Pt(IV) prodrug [Pt(5,5′-dmbpy)Cl4 and human serum albumin: Combination of spectroscopic and molecular modeling technique

The Pt(IV) complex [Pt(5,5′-dmbpy)Cl4] shows potential as an effective anti-cancer drug by binding to human serum albumin through electrostatic and Vander Waals interactions.

2017·30citations·S. Shahraki et al.·Journal of Biomolecular Structure and Dynamics

Journal of Biomolecular Structure and Dynamics

DOI: 10.1039/C6RA17322E

Synthesis, characterization, in vitro cytotoxicity, in silico ADMET analysis and interaction studies of 5-dithiocarbamato-1,3,4-thiadiazole-2-thiol and its zinc(II) complex with human serum albumin: combined spectroscopy and molecular docking investigations

The Zn complex of 5-dithiocarbamato-1,3,4-thiadiazole-2-thiol shows significant cytotoxic activity against MCF-7 breast cancer cells and shows promising interaction with human serum albumin.

2016·23citations·Fereshteh Shiri et al.·RSC Advances

RSC Advances

DOI: 10.1007/s13738-015-0784-8

Characterization of the interaction between a platinum(II) complex and human serum albumin: spectroscopic analysis and molecular docking

The interaction between a platinum(II) complex and human serum albumin involves hydrophobic forces, which may help understand drug delivery and pharmacological behavior.

2016·37citations·S. Shahraki et al.·Journal of the Iranian Chemical Society

Journal of the Iranian Chemical Society

DOI: 10.1016/J.JLUMIN.2014.10.055

Study of the interaction between two newly synthesized cyclometallated platinum (II) complexes and human serum albumin: Spectroscopic characterization and docking simulation

The flexible cyclometallated platinum (II) complex C1 shows higher binding affinity and structural flexibility compared to the rigid C2, suggesting structural flexibility is crucial for designing anticancer Pt (II) complexes with improved binding affinity for human serum albumin.

2015·35citations·R. Yousefi et al.·Journal of Luminescence

Journal of Luminescence

DOI: 10.1016/j.saa.2014.08.149

Spectroscopic and molecular modeling study on the separate and simultaneous bindings of alprazolam and fluoxetine hydrochloride to human serum albumin (HSA): with the aim of the drug interactions probing.

Alprazolam and fluoxetine hydrochloride interact with human serum albumin through complex formation and binding affinity changes, with fluoxetine decreasing the binding affinity between ALP and HSA.

2015·50citations·Faeze Dangkoob et al.·Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Citations

DOI: 10.1016/j.jddst.2024.105686

In Vitro and In Vivo Evaluation of Isoxsuprine Loaded Invasomes for Efficient Treatment of Diabetes‐Accelerated Atherosclerosis

Nasal administration of IXS-loaded invasomes shows potential as an effective treatment for diabetes-accelerated atherosclerosis by increasing permeation and efficacy.

2024·8citations·H. Abou-Taleb et al.·Journal of Drug Delivery Science and Technology

Journal of Drug Delivery Science and Technology

DOI: 10.1021/acsomega.3c02552

MOFs as Versatile Catalysts: Synthesis Strategies and Applications in Value-Added Compound Production

Metal-organic frameworks (MOFs) show great potential as versatile catalysts for diverse applications, including value-added compound production and CO2 fixation, reduction, and photoelectrochemical water splitting.

2023·19citations·R. Malekshah et al.·ACS Omega

ACS Omega

DOI: 10.1016/j.aej.2023.03.068

DFT study of carboplatin encapsulation interactions with carboxylated carbon nanotubes and conjugated to folic acid for targeted nano delivery systems

Carboxylated carbon nanotubes and folic acid-coated nanotubes can enhance the therapeutic efficacy and reduce the adverse effects of the anticancer drug carboplatin.

2023·14citations·Umme Hani et al.·Alexandria Engineering Journal

Alexandria Engineering Journal

DOI: 10.1155/2022/9261683

Metal Complexes in Target-Specific Anticancer Therapy: Recent Trends and Challenges

Metal complexes-based targeted cancer therapy shows promise in reducing systemic toxicity and adverse effects while targeting cancer cells effectively.

2022·27citations·Gemechu Shumi et al.·Journal of Chemistry

Journal of Chemistry

DOI: 10.1515/tjb-2019-0284

Synthesis of 2-aminonaphthalene-1-sulfonic acid Schiff bases and their interactions with human serum albumin

Two synthesized Schiff base compounds can effectively interact with human serum albumin, potentially benefiting biomedical research applications.

2020·1citation·Huiqing Li et al.·Turkish Journal of Biochemistry

Turkish Journal of Biochemistry

DOI: 10.1016/j.saa.2019.117728

The specific binding of a new 1,2,3-triazole to three blood proteins and it's appended rhodamine complex for selective detection of Hg2.

The novel rhodamine-based fluorescent probe (REDTC) effectively detects mercury ions in biological systems, with hydrophobic forces playing a dominant role in stabilizing complexes.

2019·10citations·Guo-hua Ding et al.·Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

DOI: 10.1080/07391102.2019.1587515

Assessment on the binding affinity between ritonavir with model transport protein: a combined multi-spectroscopic approaches with computer simulation

Ritonavir (RTV) has a strong binding affinity with model transport protein BSA, preferentially fitting into sub-domain IIIA, with hydrogen bonds and van der Waals forces acting as predominant functions.

2019·12citations·Bao-li Wang et al.·Journal of Biomolecular Structure and Dynamics

Journal of Biomolecular Structure and Dynamics

DOI: 10.1080/07391102.2018.1546619

Synthesis of new ultrasonic-assisted palladium oxide nanoparticles: an in vitro evaluation on cytotoxicity and DNA/BSA binding properties

Ultrasonic-assisted palladium oxide nanoparticles show potential as an alternative to cisplatin for DNA denaturation and apoptosis in prostate cancer treatment.

2019·18citations·Ziba Sorinezami et al.·Journal of Biomolecular Structure and Dynamics

Journal of Biomolecular Structure and Dynamics

DOI: 10.1016/J.JLUMIN.2018.09.065

The spectroscopic and computational investigation on interaction of a novel 1,2,3-triazole with three globular proteins

EPTC enhances fluorescence in human serum albumin, human immunoglobulin, and bovine hemoglobin, with hydrophobic forces playing a major role in stabilizing EPTC-protein systems.

2019·2citations·Jian-ling Li et al.·Journal of Luminescence

Journal of Luminescence