C. Pouget, P. Trouillas, Rokhaya Gueye
Dec 6, 2013
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0
Influential Citations
1
Citations
Journal
Synlett
Abstract
Abstract A series of 4′-alkyl-2′-hydroxyacetophenones were prepared by Suzuki cross-coupling reactions of 4′-bromo-2′-hydroxyacetophenone. In these reactions, alkyl(trifluoro)borates were found to be better reactants than alkylboronic acids. 4′-Alkyl-2′-hydroxyacetophenones are key intermediates for the further synthesis of lipoflavonoids that are more readily incorporated into lipid bilayer membranes than flavonoids and should, therefore, have superior biological effects through increased bioavailability.