The Failing Right Ventricle in Adult Congenital Heart Disease

doi:10.1007/978-3-319-17698-7_8

Paper

The Failing Right Ventricle in Adult Congenital Heart Disease

Published 2015 · S. Westaby

UNKNOWN SJR score

0

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Given the reproducibility and success of congenital heart surgery in infancy, many patients now survive into adult life with late onset of right heart failure [1]. For these patients right ventricular function may determine symptomatic burden, quality of life and ultimate prognosis. Either naturally or following corrective surgery, the morphological right ventricle usually ejects blood into the pulmonary circulation. In the minority with transposition complexes, it may support the systemic circulation in which case the right ventricle determines longevity [2, 3]. As such this chamber can adapt and pump against systemic afterload for decades. Because of its importance in congenital heart disease, preservation of right ventricular function is increasingly in focus [4, 5].

Study Snapshot

Right ventricular function preservation is crucial for patients with adult congenital heart disease, as it determines symptom burden, quality of life, and prognosis.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

The Failing Right Ventricle in Adult Congenital Heart Disease

Sign up to use Study Snapshot

References

Adult congenital heart disease

Advances in medical, interventional, and surgical techniques have revolutionized adult congenital heart disease care, with most patients now expected to survive and thrive, but lifelong follow-up is crucial for optimal cardiac status and quality of life.

Moss and Adams' heart disease in infants, children, and adolescents : including the fetus and young adult

This book provides a comprehensive overview of heart disease in infants, children, and adolescents, covering basic concepts, pathology, diagnostic methods, and age-specific issues.

Right Ventricular Failure and Pathobiology in Patients with Congenital Heart Disease – Implications for Long-Term Follow-Up

Right ventricular dysfunction is common in patients with congenital heart defects, and understanding its pathobiology is crucial for individual care and long-term follow-up.

Differential responses of the right ventricle to abnormal loading conditions in vivo: possible pathophysiologic mechanisms.

Acetylation of Sp3 may play a role in the differential response of the right ventricle to abnormal loading conditions, potentially serving as a biomarker for right heart failure in children and adults with congenital heart disease.

Pressure‐Overload Hypertrophy of the Developing Heart Reveals Activation of Divergent Gene and Protein Pathways in the Left and Right Ventricular Myocardium

Pressure-overload hypertrophy in developing hearts activates diverse gene and protein pathways, revealing potential therapeutic targets for intervention before heart failure.

Citations