M. Zovko, B. Zorc, M. Takač
2001
Citations
0
Influential Citations
6
Citations
Journal
Acta Pharmaceutica
Abstract
Synthesis of a series of new fenoprofenamides (3a-j) is described. Amide bonding was achieved by aminolysis of fenoprofen benzotriazolide (2) with various amines: primary, secondary, hydroxylamine and amino acids. The structures of synthesised compounds were fully characterised by IR, 1 H and 13 C NMR spectroscopies and elemental analysis. The synthesised compounds are potential prodrugs of a well known NSAID fenoprofen.