The glucosinolate breakdown product indole-3-carbinol acts as an auxin antagonist in roots of Arabidopsis thaliana.

doi:10.1111/tpj.12824

Paper

The glucosinolate breakdown product indole-3-carbinol acts as an auxin antagonist in roots of Arabidopsis thaliana.

Published May 1, 2015 · E. Katz, Sophia Nisani, Brijesh Singh Yadav

The Plant journal : for cell and molecular biology

Q1 SJR score

92

Citations

4

Influential Citations

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Abstract

The glucosinolate breakdown product indole-3-carbinol functions in cruciferous vegetables as a protective agent against foraging insects. While the toxic and deterrent effects of glucosinolate breakdown on herbivores and pathogens have been studied extensively, the secondary responses that are induced in the plant by indole-3-carbinol remain relatively uninvestigated. Here we examined the hypothesis that indole-3-carbinol plays a role in influencing plant growth and development by manipulating auxin signaling. We show that indole-3-carbinol rapidly and reversibly inhibits root elongation in a dose-dependent manner, and that this inhibition is accompanied by a loss of auxin activity in the root meristem. A direct interaction between indole-3-carbinol and the auxin perception machinery was suggested, as application of indole-3-carbinol rescues auxin-induced root phenotypes. In vitro and yeast-based protein interaction studies showed that indole-3-carbinol perturbs the auxin-dependent interaction of Transport Inhibitor Response (TIR1) with auxin/3-indoleacetic acid (Aux/IAAs) proteins, further supporting the possibility that indole-3-carbinol acts as an auxin antagonist. The results indicate that chemicals whose production is induced by herbivory, such as indole-3-carbinol, function not only to repel herbivores, but also as signaling molecules that directly compete with auxin to fine tune plant growth and development.

In Vitro Study

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Study Snapshot

Indole-3-carbinol, a plant-protecting chemical, also acts as an auxin antagonist, influencing plant growth and development by inhibiting root elongation and disrupting auxin signaling.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

The glucosinolate breakdown product indole-3-carbinol acts as an auxin antagonist in roots of Arabidopsis thaliana.

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References

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Citations

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The plant genome plays a crucial role in defending against insects through multiple layers of interactions, with molecular processes regulating interactions and shaping future management strategies.

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Indole-3-carbinol inhibits root elongation in plants through antagonism of auxin signaling, with PIP5K and WAK1-3/WAK1-3/WAK1-3/WAK1-3/WAK1-3/WAK1-3/WAK1-3/WA

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Overexpression of S30 ribosomal protein in plants leads to transcriptional changes that enhance stress resistance and photomorphogenesis.

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Jasmonate research reveals that phytohormones and other bioactive metabolites are part of a diverse group of regulatory metabolites that control plant growth, development, and stress responses.