Fei Wen, Zheng Li
Aug 5, 2020
Citations
0
Influential Citations
3
Citations
Journal
Synthetic Communications
Abstract
Abstract Glycinamide hydrochloride as an inexpensive and commercially available transient directing group for the C(sp3)−H arylation of 2-methylbenzaldehydes is described. A series of practical 2-benzylbenzaldehydes bearing various functional groups are efficiently synthesized in satisfactory yield by this strategy. This method can also be extended to gram scale. Graphical Abstract