S. Viswanathan, P. T. Sambantham, K. Reddy
Feb 17, 1984
Citations
1
Influential Citations
48
Citations
Quality indicators
Journal
European journal of pharmacology
Abstract
A flavonoid, gossypin, was evaluated for its analgesic action by using acetic acid-induced writhing in mice and was compared with morphine. Gossypin inhibited writhing in a dose-dependent manner. This action was antagonised by naloxone. The pA2 values for morphine-naloxone and gossypin-naloxone were almost identical suggesting a definite involvement of opiate receptors in the analgesic action of gossypin.