Hailong He, D. Du
Apr 30, 2014
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Influential Citations
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Journal
Tetrahedron-asymmetry
Abstract
Abstract Highly enantioselective Mannich reactions of imines bearing a benzothiazole moiety with tert -butyl acetoacetate, catalyzed by a cinchona-based squaramide organocatalyst have been developed. The corresponding benzothiazole β-keto ester derivatives were obtained in high yields (up to 99%) and with excellent enantioselectivities (up to 98% ee).