D. Tai, Ching-Chong Huang, Hui-Yao Huang
Dec 1, 1993
Citations
0
Influential Citations
6
Citations
Journal
Biotechnology Letters
Abstract
SummaryEnzymatic hydrolysis of racemic 3-acetylthio-2-methylpropionic methyl ester catalyzed by bovine pancreatic protease and Mucor javanicus lipase showed opposite enantioselecivity. A tandem hydrolysis of the ester catalyzed by these two enzymes gives enantiomerically enriched (S)-3-acetylthio-2-methylpropionic acid, a building block of captopril.