I. Elkadi, M. Eman Mostafa
2008
Citations
0
Influential Citations
7
Citations
Journal
Folia Microbiologica
Abstract
Thirty-three isolates belonging to six species of the genusTrichoderma were tested for the ability to hydroxylate progesterone to 11α-, 11β-, 11α,17α- and 6β,17α-derivatives, and epicortisol.T. aureoviride, T. harzianum, T. polysporum andT. pseudokoningii produced 11α-hydroxyprogesterone.T. harzianum andT. hamatum can form only the 11β-isomer.T. koningii andT. hamatum produced 11α-,11β-, 11α,17α- and 6β,11α-hydroxy derivatives. 11α, 11β, 6β,11α- and 11α,17α-hydroxyprogesterones and epicortisol are produced byT. aureoviride andT. pseudokoningii. Cortisol was produced only when the medium was fortified by 10 g/L peptone. This is the first record of conversion of progesterone to mono-, di- and trihydroxyprogesterones by theseTrichoderma species.