Archana Sharma, Vipin Kumar, R. Kharb
May 31, 2016
Citations
0
Influential Citations
29
Citations
Quality indicators
Journal
Current pharmaceutical design
Abstract
BACKGROUND The imidazole nucleus is inimitable and ubiquitous and it is very well known to play an important role in living organisms. Imidazole derivatives are under intensive scientific exploration due to their diverse and significant pharmacological activities. METHODS The present paper is an attempt to discuss chemistry, synthetic aspects including click chemistry procedures of imidazoles through systematic literature survey. RESULTS Biological activity profiles of the imidazole derivatives reported in recent scientific literature from 2000 to 2015 have been discussed in detail. It has been found that imidazole derivatives depict appreciable antiinfective activity potential. CONCLUSION It is anticipated that the information compiled in this paper will be useful and motivating to prospective researchers working on this heterocylic scaffold.