Immunomodulatory and toxicological evaluation of the fruit seeds from Platonia insignis, a native species from Brazilian Amazon Rainforest

doi:10.1016/J.BJP.2015.05.014

Paper

Immunomodulatory and toxicological evaluation of the fruit seeds from Platonia insignis, a native species from Brazilian Amazon Rainforest

Published Feb 1, 2016 · Ana Karina Marques Fortes Lustosa, D. Arcanjo, R. Ribeiro

Revista Brasileira de Farmacognosia

Q2 SJR score

26

Citations

1

Influential Citations

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Abstract

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Non-RCT

Animal Study

Study Snapshot

The hexanic extract of Platonia insignis seeds shows low toxicity and strong immunomodulatory effects, potentially aiding in the development of effective and safe phytomedicines from Brazilian local biodiversity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Immunomodulatory and toxicological evaluation of the fruit seeds from Platonia insignis, a native species from Brazilian Amazon Rainforest

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References

Behavioral and neurochemical studies in mice pretreated with garcinielliptone FC in pilocarpine-induced seizures

Garcinielliptone FC (GFC) can reduce the frequency of pilocarpine-induced seizures by modulating GABA and glutamate contents and acetylcholinesterase activity in mice hippocampus.

Anti-inflammatory, analgesic, and immunostimulatory effects of Luehea divaricata Mart. & Zucc. (Malvaceae) bark

The hydroalcoholic crude extract of Luehea divaricata bark possesses anti-inflammatory, analgesic, and immunostimulatory properties, promoting reduction in paw edema and increased macrophage activity.

Garcinielliptone FC, a polyisoprenylated benzophenone from Platonia insignis Mart., promotes vasorelaxant effect on rat mesenteric artery

Garcinielliptone FC from Platonia insignis Mart. promotes vasorelaxation in rat mesenteric artery, likely due to its dual effect on calcium mobilization and attenuation of transmembrane calcium influx.

The potential health benefit of polyisoprenylated benzophenones from Garcinia and related genera: ethnobotanical and therapeutic importance.

Polyisoprenylated benzophenones from Garcinia fruits show potential health benefits and could be used as cytotoxic agents in drug discovery.

Cytotoxic and leishmanicidal properties of garcinielliptone FC, a prenylated benzophenone from Platonia insignis

Garcinielliptone FC, a prenylated benzophenone from Platonia insignis, possesses cytotoxic and leishmanicidal properties, making it a potential treatment for skin diseases in traditional Brazilian medicine.

Citations