Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults

doi:10.1016/j.nlm.2010.08.003

Paper

Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults

Published Oct 1, 2010 · S. Stroth, R. Reinhardt, J. Thöne

Neurobiology of Learning and Memory

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94

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5

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Abstract

Abstract removed due to Elsevier request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

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Study Snapshot

Key takeawayIncreased physical fitness improves cognitive flexibility and control in young adults, with Val/Val individuals showing greater improvements compared to Met allele carriers.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults

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References

Depression and the role of genes involved in dopamine metabolism and signalling

Genes involved in dopamine metabolism and signaling may influence susceptibility to major depressive disorder, but gene-gene interactions and gene-environment interactions are more significant.

Exercise and time-dependent benefits to learning and memory

Exercise improves cognitive performance and brain plasticity, with benefits persisting even after exercise has ended.

Attention and facilitation: converging information versus inadvertent reading in Stroop task performance.

Stroop facilitation and interference effects occur within and between languages, supporting the converging information hypothesis of Stroop facilitation.

Running enhances spatial pattern separation in mice

Running improves spatial pattern separation in adult mice, with increased neurogenesis contributing to this improvement.

The Role of COMT Val158Met in Cognition

The COMT Val158Met polymorphism has a significant impact on working memory, attentional control, and episodic memory in mice, but its role in human cognition remains unclear.

Aerobic endurance exercise benefits memory and affect in young adults

Aerobic endurance exercise, such as running for 30 minutes per week for 6 weeks, can improve visuospatial memory and positively affect in young adults, but not concentration or verbal memory.

Role of Dopamine in the Motivational and Cognitive Control of Behavior

Dopamine plays a complex role in behavioral control, with individual differences in response to dopaminergic drugs, highlighting the need for further research on its role in motivation and cognition.

Meta-Analysis of the Cognitive Effects of the Catechol-O-Methyltransferase Gene Val158/108Met Polymorphism

The COMT Val158/108Met polymorphism shows little or no association with cognitive function, and publication bias may hinder our understanding of the genetic basis of psychological functions and psychiatric disorders.

Dopamine, learning, and reward-seeking behavior.

Dopamine plays a crucial role in learning, motivation, and reward-seeking behaviors, with its dysfunction being linked to various pathological states and addictions.

Citations