R. Irgashev, N. Kazin, G. Rusinov
Jun 17, 2018
Citations
0
Influential Citations
5
Citations
Journal
Arkivoc
Abstract
A number of 5,11-dialkyl-6,12-di(hetero)aryl-5,11-dyhydroindolo[3,2-b ]carbazoles has been synthesized by modified method based on HBr catalyzed condensation of (hetero)aromatic aldehydes with indole in MeCN solution affording 5,6,11,12-tetrahydroindolo[3,2-b ]carbazoles, that have been aromatized with I 2 in DMF solution for 1 h at reflux, followed by alkylation of 5,11-dihydro compounds. New 2,8-dicyano-(10 examples) as well as 2,8-bis(benzo[ d ]thiazol-2-yl)-substituted (5 examples) derivatives of these 5,11-dyhydroindolo[3,2-b ]carbazoles have been obtained through their initial C2,8-formylation, followed by treatment of dialdehydes with excess of hydroxylamine and dehydration of the formed aldoximes with acetic anhydride or by interaction with excess of 2-aminothiophenol in DMSO solution, respectively.