Wang Si-ying
2013
Citations
0
Influential Citations
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Citations
Quality indicators
Journal
Anhui Medical and Pharmaceutical Journal
Abstract
Objective To provide a reference for developing novel anti-breast tumor drugs by study the effects of 4-hydrazino benzenesulfonic acid on proliferation of breast cancer cells.Methods Proliferation of 4-hydrazino benzenesulfonic acid MDA-MB-231 cells that SHP2 is mutated treated by were measured by MMT assay.Results 4-hydrazino benzenesulfonic acid inhibited the proliferation of MDA-MB-231 cells in a dose-depended manner while the effects on CON cells are inconspicuous.Conclusion 4-hydrazino benzenesulfonic acid has anti-proliferation effects on MDA-MB-231 cells through inhibiting SHP2 than is mutated.