Paper
Interaction of triethyl lead chloride with microtubules in vitro and in mammalian cells.
Published 1985 · Hans-Peter Zimmermann, K. Doenges, Gerhard Röderer
Experimental cell research
Q2 SJR score
43
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Triethyl lead chloride effectively depolymerizes microtubules in vitro and in vivo, leading to cell growth inhibition and the formation of binucleate cells with micronuclei.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
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Citations
Lead Stress Disrupts the Cytoskeleton Organization and Cell Wall Construction During Picea wilsonii Pollen Germination and Tube Growth
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Metal Toxicity at the Synapse: Presynaptic, Postsynaptic, and Long-Term Effects
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Folic acid, ascorbic acid and sodium selenite restore the motility of Dictyostelium discoideum inhibited by triethyllead.
Folic acid, ascorbic acid, and sodium selenite restore the motility of Dictyostelium discoideum amoebae inhibited by triethyllead, suggesting oxidative stress may play a role in TriEL's action.
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Lead disturbs microtubule organization in the root meristem of Zea mays
Lead accumulation in maize seedlings is primarily responsible for cellular toxicity due to its disruption of microtubule organization in the root meristem.
2000·248citations·S. Eun et al.·Physiologia Plantarum
Physiologia Plantarum
Voltage-activated calcium channel currents of rat dorsal root ganglion cells are reduced by trimethyl lead.
Trimethyl lead (TML) effectively reduces voltage-activated calcium channel currents in rat dorsal root ganglion cells, potentially explaining its neurotoxic effects.
1996·7citations·E. Gawrisch et al.·Toxicology letters
Toxicology letters