Theoretical investigation on antioxidant activity of bromophenols from the marine red alga Rhodomela confervoides: H-atom vs electron transfer mechanism.

doi:10.1021/jf304926m

Paper

Theoretical investigation on antioxidant activity of bromophenols from the marine red alga Rhodomela confervoides: H-atom vs electron transfer mechanism.

Published Feb 11, 2013 · A. Javan, M. J. Javan, Z. A. Tehrani

Journal of agricultural and food chemistry

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32

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1

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Abstract

Bromophenols are known as antioxidant radical scavengers for some biomolecules such as those in marine red alga. Full understanding of the role played by bromophenols requires detailed knowledge of the radical scavenging activities in probable pathways, a focus of ongoing research. To gain detailed insight into two suggested pathways, H-atom transfer and electron transfer, theoretical studies employing first principle quantum mechanical calculations have been carried out on selected bromophenols. Detailed investigation of the aforementioned routes revealed that upon H-atom abstraction or the electron transfer process, bromophenols cause an increase in radical species in which the unpaired electron appears to be delocalized as much as possible over the whole aromatic ring, especially in the bromine substituent. The O-H bond dissociation energies (BDEs) and ionization potential energies (IPs) are reported at the B3LYP level of theory, providing the first complete series of BDEs and IPs for bromophenols. The observations are compared to those of other antioxidants for which BDEs and IPs have been previously obtained.

Study Snapshot

Bromophenols from marine red alga Rhodomela confervoide exhibit antioxidant activity through H-atom abstraction or electron transfer, with radical species delocalized over the whole aromatic ring.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Theoretical investigation on antioxidant activity of bromophenols from the marine red alga Rhodomela confervoides: H-atom vs electron transfer mechanism.

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References

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Incorporating Zataria multiflora essential oil in broiler diets delays lipid peroxidation and reduces bacterial growth in raw breast meat during refrigerated storage.

Isolation, characterization, and antioxidant activity of bromophenols of the marine red alga Rhodomela confervoides.

Rhodomela confervoides marine red alga is an excellent source of natural antioxidants, with potential benefits in preventing oxidative deterioration of food.

The antioxidative effect of Iranian Mentha pulegium extracts and essential oil in sunflower oil.

Iranian Mentha pulegium water extract is a potent antioxidant, potentially protecting oil and oily products during storage.

Inhibitors of oxidation and matrix metalloproteinases, floridoside, and D-isofloridoside from marine red alga Laurencia undulata.

Floridoside and D-isofloridoside from marine red alga Laurencia undulata possess significant antioxidant capacity and potential inhibitors of MMP-2 and MMP-9, making them potential candidates for food and pharmaceutical applications.

Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata.

Urceolatin, a structurally unique bromophenol from Polysiphonia urceolata, exhibits significant DPPH radical-scavenging activity, making it a potential anti-oxidant.

Citations

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