D. Eisenmann, J. A. Yaeger
Jun 1, 1972
Citations
0
Influential Citations
17
Citations
Quality indicators
Journal
Archives of oral biology
Abstract
Abstract Fluoride and strontium are capable of inducing hypomineralized layers of rat incisor dentine. Sections containing such altered dentine were incubated in mineralizing solutions ( CaXP i = 1.6 mM 2 /l) to assess the ability of the poorly mineralized regions to take up mineral at various time intervals following injection. Microradiography and microdensitometry revealed that at all intervals (1–4 days) a substantial amount of mineral was accumulated within the hypomineralized regions. Electron microscopic examination revealed that this accumulating mineral followed the usual pattern of forming along and within the collagen fibres and was not present in the predentin. A direct relationship was found between the ability of the hypomineralized matrix to mineralize and its degree of hypomineralization. The ability of the hypomineralized dentine to mineralize in vitro soon after its formation (at a time when it is not mineralizing appreciably in vivo ) is discussed in relation to the mechanisms involved in the development of abnormally mineralized dentine.