M. Chini, P. Crotti, Lucilla Favero
Jan 17, 1994
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0
Influential Citations
147
Citations
Quality indicators
Journal
Tetrahedron Letters
Abstract
Abstract Lanthanide(III) trifluoromethanesulfonates (triflates), such as Yb(OTf) 3 , Nd(OTf) 3 and Gd(OTf) 3 , catalyze in a extraordinarily efficient way the aminolysis of 1,2-epoxides, affording the corresponding β-amino alcohols, at room temperature and in a non-protic solvent (CH 2 Cl 2 or toluene), in very good yields. The reactions are completely anti stereoselective and highly regioselective.