Visible light promoted fluoroalkylation of alkenes and alkynes using 2-bromophenol as a catalyst.

doi:10.1039/c9cc06587c

Paper

Visible light promoted fluoroalkylation of alkenes and alkynes using 2-bromophenol as a catalyst.

Published Oct 9, 2019 · Erlin Zhu, Xiao-Xiao Liu, Anwei Wang

Chemical communications

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25

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0

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Abstract

We report a new protocol for the fluoroalkylation of alkenes and alkynes by using 2-bromophenol as a catalyst. This reaction can be tailored for different reaction modes by altering the base and solvent, which feature a wide substrate scope and excellent functional group tolerance with high chemo- and regioselectivities. We further propose a mechanism involving an electron donor-acceptor (EDA) complex.

Study Snapshot

This new fluoroalkylation method using 2-bromophenol offers wide substrate scope, high chemo- and regioselectivity, and can be tailored for different reaction modes by altering base and solvent.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Visible light promoted fluoroalkylation of alkenes and alkynes using 2-bromophenol as a catalyst.

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References

Citations

Radical Perfluoroalkylation Enabled by a Catalytically Generated Halogen Bonding Complex and Visible Light Irradiation.

A substituted hydroquinone catalyst promotes radical perfluoroalkylation reactions by forming a visible light-absorbing halogen bonding complex between the catalyst and perfluoroalkyl halide radical precursor.

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