Long‐term oral atazanavir attenuates myocardial infarction‐induced cardiac fibrosis

doi:10.1016/j.ejphar.2018.03.041

Paper

DOI: 10.1016/j.ejphar.2018.03.041

Long‐term oral atazanavir attenuates myocardial infarction‐induced cardiac fibrosis

Published Jun 1, 2018 · Guanghua Zhang, Xue Zhang, Defang Li

European Journal of Pharmacology

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Rigorous Journal

Study Snapshot

Long-term oral atazanavir effectively reduces myocardial infarction-induced cardiac fibrosis in rats, likely due to blocking inflammatory cascades through an HMGB1/TLR 9 signaling pathway.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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