A. Aarnoudse, R. H. Schaik, J. Dieleman
Oct 1, 2006
Citations
5
Influential Citations
71
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Quality indicators
Journal
Clinical Pharmacology & Therapeutics
Abstract
Mefloquine, a drug used for treatment and prophylaxis of malaria, is known for its neuropsychiatric adverse effects. We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P‐glycoprotein.