Sarbjeet Kaur, Gaoyuan Zhao, Evan Busch
Feb 13, 2019
Citations
0
Influential Citations
15
Citations
Journal
Organic & biomolecular chemistry
Abstract
The organic photocatalyst (9-mesityl-10-methylacridinum tetrafluoroborate) in the presence of visible light is used to initiate thiol-ene and thiol-yne reactions. Thiyl radicals are generated upon quenching the photoexcited catalyst with a range of thiols. The highlighted mild nature of the reaction conditions allows a broad substrate scope of the reactants. Relying on this efficient metal-free condition, both thiol-ene and thiol-yne reactions between carbohydrates and peptides could be realized in excellent yields.