Modulation of adenyl cyclase action in toad bladder by chlorpropamide: antagonism to prostaglandin E.

doi:10.1016/0014-2999(73)90020-4

Paper

DOI: 10.1016/0014-2999(73)90020-4

Modulation of adenyl cyclase action in toad bladder by chlorpropamide: antagonism to prostaglandin E.

Published Jun 1, 1973 · A. Ozer, G. Sharp

European journal of pharmacology

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Abstract

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In Vitro Study

Study Snapshot

Chlorpropamide stimulates adenyl cyclase, enhances adenyl cyclase activity, and antagonizes prostaglandin E in the toad bladder, enhancing both basal and hormone-stimulated activity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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References

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Citations

DOI: 10.3389/fphys.2021.797039

The Role of Vasopressin V2 Receptor in Drug-Induced Hyponatremia

Drug-induced hyponatremia is largely caused by AQP2 upregulation from V2R-cAMP-PKA signaling in the absence of AVP stimulation.

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Neurobiology of addiction

Addiction to various drugs, such as heroin, cocaine, nicotine, alcohol, phencyclidine, and cannabis, involves similar effects on reward circuitry in the brain.

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