Paper
More efficient redox biocatalysis by utilising 1,4-butanediol as a ‘smart cosubstrate’
Published Jan 28, 2013 · S. Kara, Dominik Spickermann, Joerg H. Schrittwieser
Green Chemistry
Q1 SJR score
52
Citations
1
Influential Citations
Abstract
1,4-Butanediol is shown to be an efficient cosubstrate to promote NAD(P)H-dependent redox biocatalysis. The thermodynamically and kinetically inert lactone coproduct makes the regeneration reaction irreversible. Thereby not only the molar surplus of cosubstrate is dramatically reduced but also faster reaction rates are obtained.
Study Snapshot
1,4-Butanediol effectively promotes NAD(P)H-dependent redox biocatalysis, resulting in faster reaction rates and reduced molar surplus.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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