Yuanwei Xie, Y. Que, Tuanjie Li
Jan 27, 2015
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0
Influential Citations
33
Citations
Journal
Organic & biomolecular chemistry
Abstract
A NHC-catalyzed [4 + 2] cyclization of 2-bromo-2-enal bearing γ-H with 3-alkylenyloxindoles under mild reaction conditions gives spirocarbocyclic oxindoles containing one quaternary carbon in moderate to good yields with high diastereoselectivities. The easy availability of the starting materials, the concise assembly and the potential utilization value of the products make this strategy attractive in molecular biology and pharmacy.