Normal erythrocyte sedimentation rate with hyperfibrinogenemia in 6-sulfanilamidoindazole arthritis.

Paper

Normal erythrocyte sedimentation rate with hyperfibrinogenemia in 6-sulfanilamidoindazole arthritis.

Published 1979 · M. Miller, C. Samuelson, J. Ward

The Journal of rheumatology

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Abstract

The erythrocyte sedimentation rate (ESR) is the most frequently employed laboratory indicator of inflammatory activity. The plasma fibrinogen concentration is usually increased in inflammatory disorders and is thought to contribute to the ESR elevation, 6-sulfanilamidoindazole induced arthritis in rats produces very high plasma fibrinogen concentrations and increased blood viscosity but no change in ESR.

Study Snapshot

In 6-sulfanilamidoindazole-induced arthritis in rats, high plasma fibrinogen concentrations and increased blood viscosity do not affect the erythrocyte sedimentation rate, suggesting that hyperfibrinogenemia may contribute to inflammation without affecting the ESR.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Normal erythrocyte sedimentation rate with hyperfibrinogenemia in 6-sulfanilamidoindazole arthritis.

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